Scientific knowledge and expertise is increasingly important in support of effective decision making. In recent decades, the United States and other nations around the world have designed and put into place institutional mechanisms to better secure science advice. The Coronavirus pandemic has put these institutions to the test, offering a rare opportunity to assess their performance in the context of a global crisis. This project performs a comparative, international evaluation of mechanisms of science advice in the pandemic emergency. As the pandemic continues, the results of this research will be of potential immediate relevance to institutions that are addressing the continuing need for science advice. More broadly, this research has great potential to contribute to the continued improvement of scientific advisory practices, which will only become more important in confronting challenges of the 21st century.